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Dr. Mishra, a distinguished and successful geneticist, plant breeder and research manager served as Director, ICAR-Indian Institute of Rice Research (IIRR) formerly known as Directorate of Rice Research (DRR), Hyderabad and ICAR- Indian Institute of Wheat & Barley Research (IIWBR) formerly known as Directorate of Wheat Research ( DWR ), Karnal - the two most important crops , rice and wheat, contributing more than 75% towards National Food and Nutritional security. His contribution as Vice Chancellor, Sher-e-Kashmir University of Agricultural Sciences (SKUAST), Jammu in education, research and extension has been highly significant. He has also worked in International Rice Research Institute, Philippines and University of Sussex, UK for about three years. He coordinated the largest AICRP network on rice and 2nd largest AICRP on wheat both involving nearly more than 800 rice and wheat scientists. He was coordinator of nearly sixty five national and international research projects. His pioneering work on genetics of salinity tolerance and ion uptake in rice is well recognized worldwide. Out of several salt tolerant varieties developed by him the variety CSR 10 and Basmati rice CSR 30 have revolutionized rice production in the fragile saline / sodic soil. CSR 30 is the first Basmati variety possessing moderate salt tolerance and also adapted to normal soil has replaced the Taraori Basmati and forms the bulk of Indian traditional Basmati rice export. It occupies large area of the traditional type basmati coverage in Haryana. Dr. Mishra has made outstanding contribution in developing low-cost biological amelioration technology for salt affected soils through development and popularization of CSR 10 variety which is a substitute of chemical amendment for resource poor farmers. He has contributed in pioneering work of introgressing 3 BLB genes (xa 5, xa 13 and XA 21 ) in Sambha Mahsuri variety which has been released and under commercial cultivation. Another most significant contribution made under his leadership was the development of rice hybrids in India which has now spread from an area of 0.1 mha to more than 3.5 mha. His eleven varieties have been released by CVRC. He has facilitated the development and release of 144 rice varieties including 9 hybrids, 21 wheat, 1 triticale and 3 barley varieties suited for different ecologies. He coordinated the national gene pyramiding project, ICAR Hybrid Rice, NATP Mission Mode Project, Functional genomics, Golden Rice, Biofortification and international projects like IRRI-ADB, Indo-UK, ICAR-IRRI, CSSRI-UoS-IRRI DFID, World Bank/ EEU aided CSSRI-UPLDC, ACIAR-ICAR, Indo-Swiss (ISCB), ICAR-CIMMYT, ICAR-ICARDA etc. Novel research was initiatiated like pyramiding of rust resistance genes ( Yr 5, Yr 10, Yr 15, Lr 34, Lr 37 ) in the background of popular wheat cultivars. His role in formulating strategies to tackle threat of a new stem rust race Ug 99 was highly effective. He represented India to many countries USA, UK, Australia, China, Japan, Italy, Philippines, Mexico, France, Netherland, Spain, Vietnam, Indonesia, Thailand, Pakistan, Egypt, Australia for collaborative work. He published 539 research papers (refereed 103) of international and national repute apart from electronic publication, books and chapters. He was honored for his outstanding service to the nation by Indian Council of Agricultural Research for the development of Basmati CSR 30. He is awardee of Rafi Ahmad Kidwai Award, Hari Om Ashram Trust Award, International Year of Rice- Dr. A. K. Richharia Award, 2004, Dr. Ram Dhan Singh Memorial Award and international recognition, Senadhira Rice Research Award, IRRI, Philippines. Bharat Mata Award was also conferred on him by Indian Institute of Oriental Heritage, Kolkata. He has also served as Chairman and Member of Boards of Management, QRT, RAC, Scientific Advisory Committees, Steering Committees, Selection Committees, Academic Council, University Council etc. State-of-art facilities were created at CSSRI, IIRR, IWBRI and SKUAST of Jammu for advanced research. About 175 scientists were trained in National and International laboratories. 6078 Frontline Demonstration in rice, 3678 in wheat and 254 in barley were organized including Farmers Fairs, Kisan Divas and Exhibitions for the welfare of farmers. Overall Impact was predicted coverage of about 6 mha with production of around 20 mt contributing more than Rs 192 billion / year.