Indian Society of Genetics & Plant Breeding

Mutagenicity of a new dimethyl nitroso compound in pea (Pisum sativum L.)

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A new nitroso-urea compound (nitroso dimethyl urea,
NDMU) with two methyl groups was tested in two pea
varieties (Early Superb and Mahndofer) under seed
treatment with 0.02% concentration applied for 6 hours
and compared with its single methyl analogue, N-nitroso
methyl urea (NMU). The variety Early Superb was less
mutable (mutation rate 2.1%) than Mahndorfer (13.3%).
NDMU had slightly superior mutagenicity (7.3% mutations)
over NMU (6.1%), although the new mutagen is much
less toxic than NMU. Thus, the mutation rates can be
further enhanced with higher doses of NDMU, which makes
it particularly suitable for· mutagenesis in higher plants.

Keywords: Nitroso dimethyl urea, NDMU, toxicity, mutagenicity, pea


Year: 2001
Volume: 61
Issue: 3
Article DOI: NA
Print ISSN: 0019-5200
Online ISSN: 0975-6906



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