Indian Society of Genetics & Plant Breeding

Multiple roles of a PLCĪ² regulator in olfaction, pupal development and synaptic vesicle recycling in Drosophila melanogaster

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G-protein coupled Phospholipase-C-β (PLCβ) signaling
and its various components are vital to the regulation of
development and behaviour of Drosophila. The gene stmA
(CG8739) was first characterized as a temperature
sensitive paralytic mutant and recently identified as a
regulator of PLCβ in G-protein signaling. It alters
membrane phospholipid levels and affects visual
transduction. The present study establishes the role of
stmA in olfaction, pupal development and synaptic vesicle
recycling in Drosophila. Interaction between stmA and
genes for the inositol triphosphate receptor (itpr) and for
endocytosis and exocytosis in synaptic vesicles is also
shown.
 

Keywords: Drosophila, olfaction, pupation, G-protein, itpr

Info

Year: 2010
Volume: 70
Issue: 3
Article DOI: N/A
Print ISSN: 0019-5200
Online ISSN: 0975-6906

Authors

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Shanti Chandrashekaran info_circle

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