Dominant temperature sensitive lethals (DTSLs) and semilethals were induced by EMS on
the SM5 balancer of Drosophila melanogaster at the rate of 0.0025. SM5 DTSL4 is a fully
penetrant line with 1000/. lethality at the nonpermissive temperature of 2S°C. At the
permissive temperature (l9°C) it shows normal fertility and survival. DTSL4 is basically a
pupal lethal but exerts strong paternal influence over embryonic and larval development.
DTSL4 does not alter the recombination suppression properties of SM5. Individuals
homozygous for second chromosome loci can now be generated with ease from SM5
DTSL4/+ parents at 2S°C.
Keywords: Dominant temperaturesensitive lethal (DTSLl, balancerchromosome, Drosophila.
Article DOI: NA
Print ISSN: 0019-5200
Online ISSN: 0975-6906
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